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一般描述
主要为细胞工作设计,在匀浆后细胞核保持完整。全玻璃结构。每一套配有两根研杵。大间隙研杵用于初始样本降解。小间隙研杵用于最终匀浆。
特点和优势
• Manufactured from borosilicate glass 3.3• Designed primarily for cellular work where the nucleus remains intact after homogenization.• All-glass construction• Two pestles are supplied with each complete unit• Large clearance pestle is used for the initial sample reduction• Small clearance pestle is used to form the final homogenate• Replacement components are available and completely interchangeable
法律信息
KIMBLE is a registered trademark of DWK Life Sciences
Frontiers in bioengineering and biotechnology, 8, 564057-564057 (2020-10-20)
Retina is a crucial tissue for capturing and processing light stimulus. It is critical to describe the characteristics of retina at the single-cell level for understanding its biological functions. A variety of abnormalities in terms of morphology and function are
Nature neuroscience, 23(6), 701-706 (2020-04-29)
The role of non-neuronal cells in Alzheimer's disease progression has not been fully elucidated. Using single-nucleus RNA sequencing, we identified a population of disease-associated astrocytes in an Alzheimer's disease mouse model. These disease-associated astrocytes appeared at early disease stages and
Nature methods, 14(10), 955-958 (2017-08-29)
Single-nucleus RNA sequencing (sNuc-seq) profiles RNA from tissues that are preserved or cannot be dissociated, but it does not provide high throughput. Here, we develop DroNc-seq: massively parallel sNuc-seq with droplet technology. We profile 39,111 nuclei from mouse and human
G3 (Bethesda, Md.), 10(5), 1647-1655 (2020-03-07)
Long interspersed element-1 retrotransposons (LINE-1 or L1) are ∼6 kb mobile DNA elements implicated in the origins of many Mendelian and complex diseases. The actively retrotransposing L1s are mostly limited to the L1 human specific (L1Hs) transcriptional active (Ta) subfamily.
Clinical epigenetics, 12(1), 32-32 (2020-02-20)
Hexanucleotide repeat expansions of the G4C2 motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Tissues from C9ALS/FTD patients and from mouse models of ALS
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