09935
Ammonium pyrrolidinedithiocarbamate
purum p.a., ≥98.0% (NT)
Recommended Products
grade
purum p.a.
Quality Level
Assay
≥98.0% (NT)
form
(powder or powder with lumps)
mp
153-155 °C (lit.)
cation traces
Bi: ≤10 mg/kg
Ca: ≤10 mg/kg
Cd: ≤10 mg/kg
Co: ≤10 mg/kg
Cr: ≤10 mg/kg
Cu: ≤10 mg/kg
Fe: ≤10 mg/kg
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤10 mg/kg
Na: ≤50 mg/kg
Ni: ≤10 mg/kg
Pb: ≤10 mg/kg
Zn: ≤10 mg/kg
SMILES string
N.SC(=S)N1CCCC1
InChI
1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key
MDDIUTVUBYEEEM-UHFFFAOYSA-N
Gene Information
human ... RELA(5970)
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Related Categories
Application
Other Notes
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How can I dissolve Product 09935, Ammonium pyrrolidinedithiocarbamate?
Ammonium pyrrolidinedithiocarbamate is soluble in water at a concentration of approximately 50 mg/mL.
What is the solution stability of Product 09935, Ammonium pyrrolidinedithiocarbamate?
Sigma has not evaluated the solution stability of PDTC. However, aqueous stock solutions may be stable for at least one month when stored at -20 °C.
What are some functions reported for Product 09935, Ammonium pyrrolidinedithiocarbamate?
PDTC has been reported to repress vascular cell adhesion molecule-1 (VCAM-1) activation by Interleukin-1β in cultured human umbilical vein endothelial calls. Marui, M., et al., J. Clin. Invest, 92, 1866 (1993). It inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Sherman, M.P., et al., Biochem. Biophys. Res. Commun. 191, 1301-1308 (1993). It is an Inhibitor of nuclear factor kappa B., Eberhardt, et al. Biochem. Biophys. Res. Commun. 200, 163 (1994). PDTC at 100 μM, totally inhibited the NF-kappa B response in intact cells. Schreck, R., et al., J. Exp. Med. 175 , 1181-1194 (1992). It activates cAMP-dependent protein kinase (PKA) in a colorectal cancer cell line. Chinery, R., et al., J. Biol. Chem., 272, 30356 - 30361, (1997).
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