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Merck
CN

C6154

Sigma-Aldrich

Z-Gln-Gly

γ-glutamyl donor substrate

别名:

N2-[(phenylmethoxy)carbonyl]-L-glutaminyl-glycine

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About This Item

经验公式(希尔记法):
C15H19N3O6
CAS号:
分子量:
337.33
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

质量水平

表单

powder

储存温度

−20°C

SMILES字符串

NC(=O)CCC(NC(=O)OCc1ccccc1)C(=O)NCC(O)=O

InChI

1S/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)

InChI key

SOUXAAOTONMPRY-UHFFFAOYSA-N

Amino Acid Sequence

Z-Gln-Gly

应用

用于分光光度法测定转谷氨酰胺酶(TGase)活性的γ--谷氨酰胺供体底物。 Z-Gln-Gly用于酶促合成N-连接的拟糖蛋白。

生化/生理作用

N-苄氧基羰基-L-谷氨酰胺甘氨酸(Z-Gln-Gly,Z-QG)可用作底物来区分和表征转谷氨酰胺酶(TGase),该酶催化含Gln和Lys的肽的翻译后共价交联。Z-QG通过表面修饰支持谷氨酰基水平的交联应用。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Momoko Kitaoka et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(19), 5387-5392 (2011-04-07)
A new synthetic strategy for DNA-enzyme conjugates with a novel architecture was explored using a natural cross-linking catalyst, microbial transglutaminase (MTG). A glutamine-donor substrate peptide of MTG was introduced at the 5-position on the pyrimidine of deoxyuridine triphosphate to prepare
Syeda Warisul Fatima et al.
Bioresource technology, 287, 121391-121391 (2019-05-12)
This work studied the production of Transglutaminase (TGase) using wheat bran as carbon source. The medium components and culture conditions were optimized by statistical Box-Behnken response surface methodology. The release of active Transglutaminase was enhanced by adding (i) protease to
Rui P Queirós et al.
Food research international (Ottawa, Ont.), 115, 73-82 (2019-01-03)
Microbial transglutaminase (MTG) is an enzyme largely used in the food industry, mainly to improve food texture. However, many globular proteins show low susceptibility to the action of this enzyme. High-pressure processing (HPP), being able to change protein conformation, may
Dongdong Mu et al.
Applied microbiology and biotechnology, 102(13), 5533-5543 (2018-04-25)
Microbial transglutaminase (MTG) from Streptomyces mobaraensis has been widely used for crosslinking proteins in order to acquire products with improved properties. To improve the yield and enable a facile and efficient purification process, recombinant vectors, harboring various heterologous signal peptide-encoding
Ahmed Besheer et al.
Journal of pharmaceutical sciences, 98(11), 4420-4428 (2009-01-22)
Polymer-drug and polymer-protein conjugates are promising candidates for the delivery of therapeutic agents. PEGylation, using poly(ethylene glycol) for the conjugation, is now the gold standard in this field, and some PEGylated proteins have successfully reached the market. Hydroxyethyl starch (HES)

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