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Merck
CN

L6026

Sigma-Aldrich

十二烷基硫酸钠

BioXtra, ≥99.0% (GC)

别名:

SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠

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About This Item

线性分子式:
CH3(CH2)11OSO3Na
CAS号:
分子量:
288.38
Beilstein:
3599286
EC 号:
MDL编号:
UNSPSC代码:
12161900
eCl@ss:
39093306
PubChem化学物质编号:
NACRES:
NA.21

生物来源

synthetic (oragnic)

质量水平

描述

anionic

产品线

BioXtra

检测方案

≥99.0% (GC)

形式

powder

分子量

micellar avg mol wt 18,000

聚集数

62

杂质

Insoluble matter, passes filter test

缺失

≤0.5% loss on drying, HV, 20-25 °C

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

转变温度

cloud point >100 °C

溶解性

H2O: 0.1 M, clear, colorless

密度

0.496 g/cm3

痕量阴离子

chloride (Cl-): ≤0.05%
phosphate (PO43-): ≤0.0001%

痕量阳离子

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

吸光度

≤0.05 at 280 in H2O at 0.1 M
≤0.08 at 260 in H2O at 0.1 M

HLB

40

SMILES字符串

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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一般描述

十二烷基硫酸钠(SDS)是一种众所周知的阴离子去污剂,在科学研究中广泛用于蛋白质二级和三级结构的变性。它包含一条12个碳原子的非极性链,末端为带负电的硫酸基团。SDS有助于蛋白质的变性和增溶,它是聚丙烯酰胺凝胶电泳等过程的基本试剂,在凝胶电泳中有助于测定蛋白质分子量。此外,SDS可作为一种有机钠盐,并可充当去污剂和蛋白质变性剂的双重角色。它的独特性质在于阴离子表面活性剂的性质,特征在于带负电荷。这种电荷促进了与蛋白质和脂质的相互作用,从而导致胶束结构的形成。这些胶束是SDS能够有效溶解和稳定蛋白质和脂质的关键,便于研究人员在科学研究中对其进行详细研究和处理。SDS的两亲特性来源于一条带负电硫酸根的长链脂肪基团,这种性质使其成为各种生物分子实验和研究中的重要去污剂。

应用

十二烷基硫酸钠已用作:
  • 通过表面等离子体共振评估细胞色素c亲和力的表面活性剂
  • 颗粒增强免疫测定的表面活性剂,以抑制颗粒聚集并增强单个微球偶联
  • 生物膜破坏剂。

阴离子洗涤剂

特点和优势

  • 经测试证实重金属污染浓度低,从而确保其适用于各种应用
  • 经测试含痕量阴离子和阳离子
  • 适用于生物化学研究的高纯度产品

其他说明

如需了解生化试剂系列的更多信息,请填写此表

象形图

CorrosionExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 2

闪点(°F)

338.0 °F

闪点(°C)

170 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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