59924
聚山梨酯80
tested according to Ph. Eur.
别名:
吐温80(TWEEN® 80), 吐温 80, POE (20)山梨糖醇酐单油酸酯, 聚乙二醇山梨醇酐单油酸酯, 聚山梨酯 80, 聚氧乙烯山梨糖醇酐单油酸酯
产品名称
聚山梨酯80, tested according to Ph. Eur.
InChI
1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
SMILES string
CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
InChI key
RGPBUVUVZKQNHD-MDZDMXLPSA-N
agency
USP/NF
tested according to Ph. Eur.
vapor pressure
<1 mmHg ( 20 °C)
description
non-ionic
form
liquid
mol wt
average mol wt 79,000
aggregation number
60
refractive index
n20/D 1.472 (lit.)
CMC
0.012
transition temp
cloud point 65 °C
density
1.064 g/mL at 25 °C (lit.)
HLB
15
application(s)
pharmaceutical (small molecule)
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
聚山梨醇酯 80 已用于药物（雷帕霉素）治疗并用于研究雷帕霉素对骨质溶解和肿瘤生长的影响。也已用于制备喷雾干燥的乳液和用于研究抗菌功效。
Biochem/physiol Actions
聚山梨酯可用作乳化剂、溶解剂和稳定剂，用于精油、局部应用和医疗输液（含静脉、皮下和肌肉给药）。
General description
聚山梨酯 80是一种表面活性剂。聚山梨酸酯是山梨醇和山梨醇酐油酸酯通过聚乙二醇链结合。
Legal Information
TWEEN is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases
Hussein O, et al.
Cancer letters, 314(2), 176-184 (2012)
Yuan Li et al.
Frontiers in microbiology, 11, 1450-1450 (2020-07-17)
Radiation therapy is a cornerstone of modern management methods for malignancies but is accompanied by diverse side effects. In the present study, we showed that food additives such as polysorbate 80 (P80) exacerbate irradiation-induced gastrointestinal (GI) tract toxicity. A 16S
Osteolysis and pain due to experimental bone metastases are improved by treatment with rapamycin
Abdelaziz DM, et al.
Breast Cancer Research and Treatment, 143(2), 227-237 (2014)
Enhancing the antibacterial efficacy of isoeugenol by emulsion encapsulation
Nielsen CK, et al.
International Journal of Food Microbiology, 229, 7-14 (2016)
Priya N O Kasimbeg et al.
Journal of pharmaceutical sciences, 108(1), 155-161 (2018-10-14)
Characterizing protein aggregates in the presence of silicone oil is a long standing challenge for the pharmaceutical industry. Silicone oil is often used as a lubricant in devices that deliver and store therapeutic protein products and has been linked to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持