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Merck
CN
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文件

33-016

Sigma-Aldrich

PI3-激酶 HTRF ®含量测定；384 孔

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

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UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

100

种属反应性

human, mouse

制造商/商品名称

HTRF®
Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

NM_006218.2

UniProt登记号

P42336

检测方法

fluorometric (HTRF)

运输

dry ice

基因信息

human ... PIK3CA(5290)

应用

用于检测/量化：PI 3-激酶

生化/生理作用

靶标亚家族：PI3K/PI4K

包装

试剂盒容量：384孔

组分

4X反应缓冲液

PIP2（底物；1mM储备液）

终止试剂A

终止试剂B

DM A检测试剂

DM B检测试剂

DM C检测试剂

法律信息

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
Qin Li et al.
Toxicology research, 8(3), 353-360 (2019-06-05)
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-allergic symptoms. To explore the

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