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Dear Customer:

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If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN

914800

Sigma-Aldrich

Hyaluronic acid methacrylate

Degree of substitution: 10% - 30%, Mw 170,000-250,000

别名:

HA MA, HA methacrlate, Hyaluronic acid MA, Hyaluronic acid methacrlate high mol. weight

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About This Item

线性分子式:
(NaC20H28NO15)n
UNSPSC代码:
12352106
NACRES:
NA.23

价格与库存信息目前不能提供

质量水平

描述

NMR: Conforms to structure

表单

(powder or chunk(s) or fibers)

分子量

Mw 170,000-250,000

颜色

white to off-white

储存温度

2-8°C

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1 of 4

此商品
7724952411843443
Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

refractive index

n20/D 1.3 (lit.)

refractive index

n20/D 1.3 (lit.)

refractive index

n20/D 1.3 (lit.)

refractive index

-

density

1.645 g/mL at 25 °C (lit.)

density

1.645 g/mL at 25 °C (lit.)

density

1.645 g/mL at 25 °C (lit.)

density

1.65 g/cm3 at 20 °C

bp

120 °C/755 mmHg (lit.)

bp

120 °C/755 mmHg (lit.)

bp

120 °C/755 mmHg (lit.)

bp

121 °C/1013 mbar

form

liquid

form

liquid

form

liquid

form

liquid

应用

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cindy Chung et al.
Tissue engineering. Part A, 15(2), 243-254 (2009-02-06)
Mesenchymal stem cells (MSCs) are multipotent progenitor cells whose plasticity and self-renewal capacity have generated significant interest for applications in tissue engineering. The objective of this study was to investigate MSC chondrogenesis in photo-cross-linked hyaluronic acid (HA) hydrogels. Because HA
Bin Duan et al.
Acta biomaterialia, 9(8), 7640-7650 (2013-05-08)
Bioactive and biodegradable hydrogels that mimic the extracellular matrix and regulate valve interstitial cells (VIC) behavior are of great interest as three-dimensional (3-D) model systems for understanding mechanisms of valvular heart disease pathogenesis in vitro and the basis for regenerative
Judy Yeh et al.
Biomaterials, 27(31), 5391-5398 (2006-07-11)
Encapsulation of mammalian cells within hydrogels has great utility for a variety of applications ranging from tissue engineering to cell-based assays. In this work, we present a technique to encapsulate live cells in three-dimensional (3D) microscale hydrogels (microgels) of controlled
Liming Bian et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(25), 10117-10122 (2013-06-05)
Methacrylated hyaluronic acid (HA) hydrogels provide a backbone polymer with which mesenchymal stem cells (MSCs) can interact through several cell surface receptors that are expressed by MSCs, including CD44 and CD168. Previous studies showed that this 3D hydrogel environment supports
Aleksander Skardal et al.
Tissue engineering. Part A, 16(8), 2675-2685 (2010-04-15)
Bioprinting by the codeposition of cells and biomaterials is constrained by the availability of printable materials. Herein we describe a novel macromonomer, a new two-step photocrosslinking strategy, and the use of a simple rapid prototyping system to print a proof-of-concept

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Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

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