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Merck
CN
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安全信息

285269

Sigma-Aldrich

(+)-荷包牡丹碱

98%

别名:

虎胆碱

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About This Item

经验公式（希尔记法）:
C20H17NO6
CAS号:
485-49-4
分子量:
367.35
Beilstein:
98786
MDL编号:
MFCD00005006
UNSPSC代码:
12352005
PubChem化学物质编号:
329753220

方案

98%

SMILES字符串

[H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@@]4([H])N(C)CCc5cc6OCOc6cc45

InChI

1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

InChI key

IYGYMKDQCDOMRE-ZWKOTPCHSA-N

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生化/生理作用

(+)-荷包牡丹碱是一种 GABAA 受体拮抗剂。

法规信息

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分析证书(COA)

Lot/Batch Number
26818EF
02229HF
13312KG
10419MZ
03401BY

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Motor tics, a cardinal symptom of Tourette syndrome (TS), are hypothesized to arise from abnormalities within cerebro-basal ganglia circuits. Yet noninvasive neuroimaging of TS has previously identified robust activation in the cerebellum. To date, electrophysiological properties of cerebellar activation and
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Yu-Cheng Ho et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(18), 7825-7836 (2013-05-03)
Neuropathic pain, a chronic pain due to neuronal lesion, remains unaltered even after the injury-induced spinal afferent discharges have declined, suggesting an involvement of supraspinal dysfunction. The midbrain ventrolateral periaqueductal gray (vlPAG) is known to be a crucial supraspinal region
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(47), 18661-18671 (2013-11-22)
G-protein-coupled receptors (GPCRs) may form heteromeric complexes and cooperatively mediate cellular responses. Although heteromeric GPCR complexes are suggested to occur in many neurons, their contribution to neuronal function remains unclear. We address this question using two GPCRs expressed in cerebellar
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