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Merck
CN

202398

Sigma-Aldrich

聚(乙二醇)

greener alternative

average Mn 400, hydroxyl

别名:

PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.23

product name

聚(乙二醇), average Mn 400

形式

viscous liquid

质量水平

分子量

Mn 380-420
average Mn 400

环保替代产品特性

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

折射率

n20/D 1.466

pH值(酸碱度)

4.5-7.5

粘度

7.3 cSt(210 °F)(lit.)

mp

4-8 °C (lit.)

密度

1.128 g/mL

Ω端

hydroxyl

α端

hydroxyl

环保替代产品分类

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是一种合成亲水性生物相容聚合物,在生物医学和其他应用中广泛使用。PEG无毒、经FDA批准、通常无免疫原性,常用于许多生物医学应用,包括生物结合、药物递送、表面官能化和组织工程设计。在药物递送应用中,PEG可用作抗体-药物偶联物(ADC)的接头或用作纳米粒子的表面包膜,以改善全身性药物递送。

应用

可与炭黑结合使用形成导电复合材料。 可利用聚(乙二醇)的聚合物纳米球进行药物递送。
聚乙二醇(PEG)已被用作对猪主动脉平滑肌细胞(PAOSMC)上的磁性细菌纤维素(MBC)防护膜进行合成和体外安全性评估的包膜剂。PEG为细胞培养提供了相容的表面,因为未包膜的氧化铁NP公认具有细胞毒性。在研究聚乙烯吡咯烷酮微针使用猪皮、成年人类皮肤类似物和人类包皮等经皮递送功能性胶原的有效性时,它还被用作增塑剂。据报道,此类微针通过各种分析和生物分析技术进行了鉴定。

法律信息

Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves


分析证书(COA)

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Changxin Wan et al.
Cancer research, 81(1), 158-173 (2020-11-08)
Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in HGSC are unknown. Here we performed immune functional and single-cell RNA sequencing transcriptional profiling on novel
Akashi, M., Akagi, T.
Yuki Gosei Kaguku Kyokaishi, 65, 520-520 (2004)
Ruth Hernandez-Perez et al.
Physical review. E, 96(6-1), 062803-062803 (2018-01-20)
The evaporation of droplets can give rise to a wide range of interesting phenomena in which the dynamics of the evaporation are crucial. In this work, we find simple scaling laws for the evaporation dynamics of axisymmetric droplets pinned on
Synthesis and in vitro safety assessment of magnetic bacterial cellulose with porcine aortic smooth muscle cells
Pastrana FH, et al.
Journal of Biomedical Materials Research Part A, 104(11), 2801-2809 (2016)
Transdermal delivery of functional collagen via polyvinylpyrrolidone microneedles
Sun W, et al.
Annals of Biomedical Engineering, 43(12), 2978-2990 (2015)

相关内容

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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