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Merck
CN

ATP1A1

ATPase, Na+/K+ transporting, alpha 1 polypeptide

别名:
物种:
Human ATP1A1 (476), Mouse Atp1a1 (11928), Rat Atp1a1 (24211), domestic cat ATP1A1 (101083695), Horse ATP1A1 (100034139), dog ATP1A1 (403992), chicken ATP1A1 (396530), Domestic Rabbit ATP1A1 (100302415), sheep ATP1A1 (443381), cow ATP1A1 (282144) ...展开
UniProtKB ID:
P05023, B2RBR6, B7Z2T5, B7Z3U6, F5H3A1, Q16689, Q6LDM4, Q9UCN1
基因ID:
  • Human(476) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(11928) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Rat(24211) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic cat(101083695) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Horse(100034139) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • dog(403992) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • chicken(396530) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Domestic Rabbit(100302415) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • sheep(443381) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • cow(282144) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • naked mole-rat(101697634) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic guinea pig(100192382) ATPase, Na+/K+ transporting, alpha 1 polypeptide

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Small Molecule - Activator

货号
说明
物种
D9404
洋地黄毒苷配基, ,
物种
rat

Antibodies

货号
说明
物种反应性
应用
A276
单克隆抗-Na+/K+ ATPase（α亚基） 小鼠抗, clone M7-PB-E9, ascites fluid,
物种反应性
bovine, canine, chicken, human, mouse, pig, sheep
应用
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
06-520
抗-Na+/K+ ATPase α-1抗体, Upstate®, from rabbit,
物种反应性
bovine, human, rat
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
06-172-I
Anti-Na+/K+ ATPase alpha-3, from rabbit,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
ZMS1029
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
xenopus, canine, human, monkey, mouse, porcine, rabbit, rat, sheep
应用
immunocytochemistry
immunohistochemistry
western blot
SAB5701012
Anti-Na+/K+-ATPase antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
D5878
洋地黄毒苷, ≥92% (HPLC), powder,
物种
human
D6003
地高辛, analytical standard,
物种
human
PHR1771
地高辛, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1200000
地高辛, United States Pharmacopeia (USP) Reference Standard,
物种
human
1199002
洋地黄毒苷, United States Pharmacopeia (USP) Reference Standard,
物种
human

Proteins

货号
说明
物种
A7510
腺苷 5'-三磷酸酶 来源于猪大脑皮质, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
物种

esiRNA

货号
说明
物种
EHU080631
MISSION® esiRNA, targeting human ATP1A1,
物种
human
EMU045941
MISSION® esiRNA, targeting mouse Atp1a1,
物种
mouse