Skip to Content
Merck
CN
  • Sonochemistry: a good, fast and clean method to promote the synthesis of 5-arylidene-2,4-thiazolidinediones.

Sonochemistry: a good, fast and clean method to promote the synthesis of 5-arylidene-2,4-thiazolidinediones.

Ultrasonics sonochemistry (2014-05-17)
Bruna B Drawanz, Camila S Ribeiro, Hellen G Masteloto, Patrícia D Neuenfeldt, Claudio M P Pereira, Geonir M Siqueira, Wilson Cunico
ABSTRACT

The efficient synthesis of sixteen 5-arylidene-2,4-thiazolidinediones by aldol condensation reaction of 2,4-thiazolidinedione, mono- and di-substituted arenealdehydes and KOH using ultrasound irradiation is reported. The desired compounds were obtained in a few min (10-30 min) with moderate to good yields (25-81%).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2,4-Thiazolidinedione, technical grade, 90%