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  • Short-term exposure to dimethylformamide and the impact on digestive system disease: an outdoor study for volatile organic compound.

Short-term exposure to dimethylformamide and the impact on digestive system disease: an outdoor study for volatile organic compound.

Environmental pollution (Barking, Essex : 1987) (2014-04-22)
Cui Wang, Canke Huang, Yumei Wei, Qi Zhu, Weili Tian, Qingyu Zhang
ABSTRACT

Occupational and experimental studies have revealed the organs most affected by dimethylformamide (DMF) are liver and gastrointestinal tract. However, few studies have focused on the potential effect of outdoor pollution of DMF. This study examined the health risk of hospitalization due to digestive system disease by time series studies in a case city Longwan, China. The urine metabolite of DMF was correlated well with DMF exposure concentration (EC). A 101.0-μg/m(3) (interquartile range) increase in the two-day moving average of DMF EC was associated with a 1.10 (1.01 ˜ 1.20), 1.22 (1.10 ˜ 1.35), and 1.05 (0.90 ˜ 1.22) increase in hospitalization for total digestive system diseases, liver disease, and gastrointestinal tract disease, respectively. The exposure-dose response between DMF and the relative risk of liver disease was linear only below 350 μg/m(3). These findings highlight a previously unrecognized health problem related to VOCs released into the outdoor environment.

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N,N-Dimethylformamide, anhydrous, 99.8%
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N,N-Dimethylformamide, for molecular biology, ≥99%
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Supelco
N,N-Dimethylformamide, analytical standard
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330 mg
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N,N-Dimethylformamide, ACS reagent, ≥99.8%
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330 mg
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N,N-Dimethylformamide, suitable for HPLC, ≥99.9%
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330 mg
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N,N-Dimethylformamide, ReagentPlus®, ≥99%
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330 mg
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N,N-Dimethylformamide, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.8% (GC)
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330 mg
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N,N-Dimethylformamide, biotech. grade, ≥99.9%
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330 mg
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USP
Residual Solvent Class 2 - N,N-Dimethylformamide, United States Pharmacopeia (USP) Reference Standard
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330 mg
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¥436.55