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  • Effect of human urinary trypsin inhibitor on granulocyte elastase activity.

Effect of human urinary trypsin inhibitor on granulocyte elastase activity.

Research communications in chemical pathology and pharmacology (1987-02-01)
M Ogawa, S Nishibe, T Mori, S Neumann
ABSTRACT

A human urinary trypsin inhibitor preparation, MR-20, strongly inhibited granulocyte elastase activity. The concentration of MR-20 causing 50% inhibition of the hydrolysis of Suc(Ala) 3pNA by granulocyte elastase was estimated to be 6.4 X 10(-8) M (11 U/ml).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
N-Succinyl-Ala-Ala-Ala-p-nitroanilide, elastase substrate