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  • Hybrid BaYbF(5) nanoparticles: novel binary contrast agent for high-resolution in vivo X-ray computed tomography angiography.

Hybrid BaYbF(5) nanoparticles: novel binary contrast agent for high-resolution in vivo X-ray computed tomography angiography.

Advanced healthcare materials (2012-11-28)
Yanlan Liu, Kelong Ai, Jianhua Liu, Qinghai Yuan, Yangyang He, Lehui Lu
ABSTRACT

A novel CT contrast agent denoted as BaYbF(5) @SiO(2) @PEG is presented. The as-prepared nanoparticles exhibit significantly enhanced contrast efficacy relative to clinical iodinated agents and maintain higher X-ray attenuation at different voltages, suitable for diagnostic imaging of various patients. Prolonged circulation time in vivo and low toxicity mean the nanoparticles perform excellently in in-vivo X-ray CT angiography.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ytterbium, powder, ≥99.9% trace rare earth metals basis
Sigma-Aldrich
Barium fluoride, precipitated, 99.95% trace metals basis
Sigma-Aldrich
Ytterbium(III) fluoride, anhydrous, powder, 99.98% trace metals basis
Sigma-Aldrich
Barium fluoride, 99.99% trace metals basis
Sigma-Aldrich
Barium fluoride, powder, 98%