- Stable, Well-Defined Nickel(0) Catalysts for Catalytic C-C and C-N Bond Formation.
Stable, Well-Defined Nickel(0) Catalysts for Catalytic C-C and C-N Bond Formation.
ACS catalysis (2018-08-07)
Alex J Nett, Santiago Cañellas, Yuki Higuchi, Michael T Robo, Jeanne M Kochkodan, M Taylor Haynes, Jeff W Kampf, John Montgomery
PMID30079273
ABSTRACT
The synthesis and catalytic activity of several classes of NHC-Ni(0) pre-catalysts stabilized by electron-withdrawing alkenes are described. Variations in the structure of fumarate and acrylate ligands modulate the reactivity and stability of the NHC-Ni(0) pre-catalysts and lead to practical and versatile catalysts for a variety of transformations. The catalytic activity and efficiency of representative members of this class of catalysts have been evaluated in reductive couplings of aldehydes and alkynes and in N-arylations of aryl chlorides.