Vaccine manufacturing

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Egg-based and Cell-based Influenza Vaccine Manufacturing Methods

Influenza vaccines are commonly made using egg-based and cell-based manufacturing strategies. Find step-by-step information on the manufacturing process for each method.

Cost Modeling Vaccine Manufacturing: Estimate Production Costs for mRNA and other Vaccine Modalities

A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.

Cell Harvest, Lysis, Neutralization and Clarification of Plasmid DNA (pDNA) for mRNA, plasmid-based DNA Vaccines, and Viral Vector applications

An overview of the cell harvest, lysis, neutralization, and clarification steps used for pDNA purification along with case study and practical advice.

Vaccine Manufacturing

From early phase development, through downstream purification to large scale vaccine production: learn more about vaccine process development and application expertise.

Plasmid DNA Vaccines Manufacturing

Learn about overcoming challenges in manufacturing pDNA vaccines, including low productivity and separation issues.

Eshmuno^® Fit Custom Affinity Resin Development Services: Frequently Asked Questions

This page answers all the frequently asked questions related to our Eshmuno® Fit custom affinity resin development services.

Bioprocessing Summit

Vaccine processing evolution focuses on agile manufacturing solutions amid the COVID pandemic.

mRNA Vaccines and Therapeutics Manufacturing

mRNA vaccine technology offers rapid development and scalable manufacturing for disease prevention.

Platform Technologies to Accelerate Novel Vaccine Development and Manufacturing

In this webinar, we present a comparison of novel technologies, discuss key considerations for manufacturing, and share selected case studies for platforms such as virus-like-particles, viral vectors, plasmid DNA, and mRNA platforms.

mRNA Synthesis for the Development of Vaccines and Therapeutics

Understand how mRNA vaccines induce immunity. and read how synthetic mRNA is prepared for vaccine immunogens and other biopharmaceuticals. Find reagents for synthesis of mRNA.

Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps

This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.

BIO International

We warmly invite you to visit booth 4735 at BIO International and connect with the MilliporeSigma team.

Virus-like Particles (VLPs) Vaccine Manufacturing

VLP vaccine manufacturers must optimize upstream productivity with reliable scale-up, achieve yield and efficiency goals with robust impurity removal, maximize downstream recovery, and ensure patient safety. Merck’s integrated portfolio, regulatory and applications expertise can help address these process challenges.

Virus-Based Vaccine Manufacturing

Tailored viral vaccine manufacturing addresses virus-specific challenges through collaboration.

Viral Vector Vaccine Mfg.

A templated process produces live vector vaccines. Challenges: yield loss, filtration, aggregation, scaling. Collaboration overcomes manufacturing hurdles.

Plasmid DNA Purification Process

Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.

Protein Subunit Vaccine Manufacturing

This page provides an overview of protein subunit vaccines, which incorporate a recombinant protein fragment derived from the viral pathogen. It includes a description of the subunit vaccine manufacturing workflow and the products and technologies that are essential to ensure

Manufacturing Strategies for mRNA Vaccines and Therapeutics

mRNA technology offers therapeutic versatility; its delivery systems induce protein production for various applications.