V900750
Indole-3-carboxylic acid
Vetec™, reagent grade, 98%
Synonym(s):
β-Indolylcarboxylic acid, 3-Carboxyindole, 3-Indole formic acid, 3-Indolylcarboxylic acid, Indole-β-carboxylic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C9H7NO2
CAS Number:
Molecular Weight:
161.16
EC Number:
212-231-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
129435
MDL number:
Assay:
98%
InChI
1S/C9H7NO2/c11-9(12)7-5-10-8-4-2-1-3-6(7)8/h1-5,10H,(H,11,12)
InChI key
KMAKOBLIOCQGJP-UHFFFAOYSA-N
SMILES string
OC(=O)c1c[nH]c2ccccc12
grade
reagent grade
product line
Vetec™
assay
98%
mp
232-234 °C (dec.) (lit.)
Application
Reactant for preparation of:
- Anticancer agents
- Derivatives of amino acids and peptides
- Serotonin 5-HT4 receptor antagonists
- Primary acylureas
- Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
- Serotonin 5-HT6 antagonists
- Very Late Antigen-4 (VLA-4) sntagonists
- EphB3 receptor tyrosine kinase inhibitors
- Potential Therapeutic Agent for Alzheimer′s Disease
- Vinyl ester pseudotripeptide proteasome inhibitors
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Mu-Yang Wang et al.
Journal of integrative plant biology, 54(7), 471-485 (2012-05-26)
Camalexin (3-thiazol-2'-yl-indole) is the major phytoalexin found in Arabidopsis thaliana. Several key intermediates and corresponding enzymes have been identified in camalexin biosynthesis through mutant screening and biochemical experiments. Camalexin is formed when indole-3-acetonitrile (IAN) is catalyzed by the cytochrome P450
J Hagemeier et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(2), 753-758 (2001-01-03)
The chemical structures and accumulation kinetics of several major soluble as well as wall-bound, alkali-hydrolyzable compounds induced upon infection of Arabidopsis thaliana leaves with Pseudomonas syringae pathovar tomato were established. All identified accumulating products were structurally related to tryptophan. Most
Jamil A Shilpi et al.
Fitoterapia, 81(6), 536-539 (2010-01-26)
Phytochemical investigation of the stem bark of Trewia nudiflora led to the isolation of two new cardenolides, trewianin (1) and trewioside (2), along with scopoletin (3) and indole-3-carboxylic acid (4). Structures were established by 1D- and 2D NMR spectroscopy, HR-MS
Ferdinand S Melkonyan et al.
The Journal of organic chemistry, 73(11), 4275-4278 (2008-05-13)
A variety of N-alkylated and N-arylated derivatives of methyl 1 H-indole-3-carboxylate were synthesized efficiently via Ullmann-type intramolecular arylamination, using the CuI-K 3PO 4-DMF system. This catalytic amination procedure can be performed with good to high yields under mild conditions under
Jin-Mo Ku et al.
The Journal of organic chemistry, 72(21), 8115-8118 (2007-09-20)
An enantioselective synthetic method for (-)-cis-clavicipitic acid (1) was reported. 1 was obtained in 10 steps (99% ee and 20% overall yield) from 1H-indole-3-carboxylic acid methyl ester (9) via asymmetric phase-transfer catalytic alkylation and diastereoselective Pd(II)-catalyzed intramolecular aminocyclization as key
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service