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Merck
CN

V900558

Isopropyl myristate

Vetec™, reagent grade, 98%

Synonym(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
110-27-0
Molecular Weight:
270.45
EC Number:
203-751-4
UNSPSC Code:
12352100
PubChem Substance ID:
329829933
Beilstein/REAXYS Number:
1781127
MDL number:
MFCD00008982

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Product Name

Isopropyl myristate, Vetec™, reagent grade, 98%

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

grade

reagent grade

product line

Vetec™

assay

98%

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

awg

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7727V
WXBD9242V
WXBD6091V
WXBD2320V
WXBC8426V

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T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
Shishu Goindi et al.
International journal of pharmaceutics, 495(2), 913-923 (2015-10-13)
In this paper, we report an ionic liquid-in-water (IL/w) microemulsion (ME) formulation which is able to solubilize etodolac (ETO), a poorly water soluble drug for topical delivery using BMIMPF6 (1-butyl-3-methylimidazolium hexafluorophosphate) as IL, Tween 80 as surfactant and ethanol as
Rajbharan Yadav et al.
Antimicrobial agents and chemotherapy, 59(4), 2286-2298 (2015-02-04)
Acinetobacter baumannii is among the most dangerous pathogens and emergence of resistance is highly problematic. Our objective was to identify and rationally optimize β-lactam-plus-aminoglycoside combinations via novel mechanism-based modeling that synergistically kill and prevent resistance of carbapenem-resistant A. baumannii. We
Fahima M Hashem et al.
AAPS PharmSciTech, 12(3), 879-886 (2011-07-05)
The objective of the present study was to formulate and evaluate microemulsion systems for topical delivery of clotrimazole (CTM). The solubility of CTM in various oils was determined to select the oil phase of the microemulsion systems. Pseudoternary phase diagrams
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