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Merck
CN

V900452

Hypoxanthine

Vetec, reagent grade, 98%

Synonym(s):

6-Hydroxypurine

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About This Item

Empirical Formula (Hill Notation):
C5H4N4O
CAS Number:
Molecular Weight:
136.11
EC Number:
200-697-3
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
5811
MDL number:
Assay:
98%
Form:
powder
Solubility:
formic acid: water (2:1): 50 mg/mL, clear to slightly hazy
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grade

reagent grade

product line

Vetec

assay

98%

form

powder

solubility

formic acid: water (2:1): 50 mg/mL, clear to slightly hazy

SMILES string

O=C1NC=Nc2nc[nH]c12

InChI

1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

InChI key

FDGQSTZJBFJUBT-UHFFFAOYSA-N

Application

Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Xinyu Yu et al.
iScience, 26(1), 105725-105725 (2022-12-30)
The emergence and spread of artemisinin-tolerant malaria parasites threatens malaria control programmes worldwide. Mutations in the propeller domain of the Kelch13 protein confer Plasmodium falciparum artemisinin resistance (ART-R). ART-R is linked to the reduced susceptibility of temporary growth-arrested ring-stage parasites
Chien-Wei Hou et al.
The American journal of Chinese medicine, 40(5), 979-991 (2012-08-30)
Hyperuricemia causes gouty arthritis, kidney disease, heart disease, and other diseases. Xanthine oxidase (XOD) and urate transporters play important roles in urate homeostasis. Numerous plants have been identified as XOD inhibitors. Longan seeds are known to contain high levels of
Tomáš Tichý et al.
European journal of medicinal chemistry, 55, 307-314 (2012-08-04)
Hexadecyloxypropyl esters of acyclic nucleoside phosphonates containing guanine (G) or hypoxanthine (Hx) and a (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] [(S)-HPMP] or 2-(2-phosphonoethoxy)ethyl (PEE) acyclic moiety have been prepared. The activity of the prodrugs was evaluated in vitro against different virus families. Whereas ester derivatives of



Global Trade Item Number

SKUGTIN
V900452-25G04061833050071
V900452-5G04061833050088