V900418
Biotin
Vetec™, reagent grade, ≥99%
Synonym(s):
D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
Recommended Products
grade
reagent grade
product line
Vetec™
Assay
≥99%
form
powder
color
white to off-white
mp
231-233 °C (lit.)
storage temp.
2-8°C
SMILES string
[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChI key
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
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General description
Biotin (vitamin B7 or vitamin H) is a water-soluble B complex vitamin, which consists of an uredo ring fused by a tetrahydrothiophene ring. It is available in various foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. Biotin is also produced by the normal gut flora.
Biochem/physiol Actions
Biotin is a vital cofactor for carboxylase enzymes in several metabolic pathways. It also functions as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin assists the transfer of carbon dioxide and also sustains a steady blood sugar level. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin is required for cell growth, production of fatty acids and the metabolism of fats and amino acids.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Vitamin H and their role in ruminant: A Review
Pour HA, et al.
Annals of Biological Research, 3(4), 1929-1933 (2012)
A Review of the Use of Biotin for Hair Loss
Patel DP, et al.
Skin Appendage Disorder, 3(3), 166-166 (2017)
Adeline Huiling Loo et al.
Nanoscale, 5(17), 7844-7848 (2013-07-13)
Graphene related materials have been widely employed as highly efficient transducers for biorecognition. Here we show a conceptually new approach of using graphene oxide nanoplatelets (50 × 50 nm) as voltammetric inherently active labels for specific protein-target molecule recognition. This
A Limat et al.
Archives of dermatological research, 288(1), 31-38 (1996-01-01)
In humans and in animals, biotin deficiency causes pathological changes in the skin and its appendages. High doses of biotin may also have beneficial effects on skin, hair and fingernails in humans and animals with normal biotin status. Therefore, we
Tim J Viney et al.
Nature neuroscience, 16(12), 1802-1811 (2013-10-22)
Hippocampal sharp waves are population discharges initiated by an unknown mechanism in pyramidal cell networks of CA3. Axo-axonic cells (AACs) regulate action potential generation through GABAergic synapses on the axon initial segment. We found that CA3 AACs in anesthetized rats
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