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Merck
CN

V900418

Biotin

Vetec™, reagent grade, ≥99%

Synonym(s):

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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About This Item

Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
58-85-5
Molecular Weight:
244.31
EC Number:
200-399-3
UNSPSC Code:
12352201
PubChem Substance ID:
329829827
Beilstein/REAXYS Number:
86838
MDL number:
MFCD00005541

Key Documents

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Product Name

Biotin, Vetec™, reagent grade, ≥99%

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

grade

reagent grade

product line

Vetec™

assay

≥99%

form

powder

color

white to off-white

mp

231-233 °C (lit.)

storage temp.

2-8°C

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Biochem/physiol Actions

Biotin is a vital cofactor for carboxylase enzymes in several metabolic pathways. It also functions as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin assists the transfer of carbon dioxide and also sustains a steady blood sugar level. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin is required for cell growth, production of fatty acids and the metabolism of fats and amino acids.

General description

Biotin (vitamin B7 or vitamin H) is a water-soluble B complex vitamin, which consists of an uredo ring fused by a tetrahydrothiophene ring. It is available in various foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. Biotin is also produced by the normal gut flora.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7036V
WXBF5380V
WXBF4693V
WXBF2535V
WXBF3429V

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Vitamin H and their role in ruminant: A Review
Pour HA, et al.
Annals of Biological Research, 3(4), 1929-1933 (2012)
A Review of the Use of Biotin for Hair Loss
Patel DP, et al.
Skin Appendage Disorder, 3(3), 166-166 (2017)
Tuncay Baubec et al.
Cell, 153(2), 480-492 (2013-04-16)
To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution of chromatin-interacting factors. This enabled us to create genomic maps for the methyl-CpG-binding domain (MBD) family of proteins, including disease-relevant
Tim J Viney et al.
Nature neuroscience, 16(12), 1802-1811 (2013-10-22)
Hippocampal sharp waves are population discharges initiated by an unknown mechanism in pyramidal cell networks of CA3. Axo-axonic cells (AACs) regulate action potential generation through GABAergic synapses on the axon initial segment. We found that CA3 AACs in anesthetized rats
Adeline Huiling Loo et al.
Nanoscale, 5(17), 7844-7848 (2013-07-13)
Graphene related materials have been widely employed as highly efficient transducers for biorecognition. Here we show a conceptually new approach of using graphene oxide nanoplatelets (50 × 50 nm) as voltammetric inherently active labels for specific protein-target molecule recognition. This
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