V900396
Histamine
Vetec™, reagent grade, ≥97%
Synonym(s):
2-(4-Imidazolyl)ethylamine
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About This Item
Empirical Formula (Hill Notation):
C5H9N3
CAS Number:
Molecular Weight:
111.15
EC Number:
200-100-6
UNSPSC Code:
12352116
PubChem Substance ID:
Beilstein/REAXYS Number:
2012
MDL number:
eCl@ss:
32160406
Assay:
≥97%
grade
reagent grade
product line
Vetec™
assay
≥97%
bp
167 °C/0.8 mmHg (lit.)
mp
83-84 °C (lit.)
storage temp.
−20°C
SMILES string
NCCc1c[nH]cn1
InChI
1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI key
NTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Endogenous H1 and H2 histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Santosh K Mishra et al.
Science (New York, N.Y.), 340(6135), 968-971 (2013-05-25)
Itch is triggered by somatosensory neurons expressing the ion channel TRPV1 (transient receptor potential cation channel subfamily V member 1), but the mechanisms underlying this nociceptive response remain poorly understood. Here, we show that the neuropeptide natriuretic polypeptide b (Nppb)
Lena Böhn et al.
The American journal of gastroenterology, 108(5), 634-641 (2013-05-07)
Despite the fact that food and diet are central issues, that concern patients with irritable bowel syndrome (IBS), the current understanding about the association between the intake of certain foods/food groups and the gastrointestinal (GI) symptom pattern, psychological symptoms, and
David P Roberson et al.
Nature neuroscience, 16(7), 910-918 (2013-05-21)
The peripheral terminals of primary sensory neurons detect histamine and non-histamine itch-provoking ligands through molecularly distinct transduction mechanisms. It remains unclear, however, whether these distinct pruritogens activate the same or different afferent fibers. Using a strategy of reversibly silencing specific
Global Trade Item Number
| SKU | GTIN |
|---|---|
| V900396-5G | 04061832094236 |
| V900396-1G | 04061825983868 |