V900343
L-Arginine
≥98%, Vetec™
Synonym(s):
(S)-2-Amino-5-guanidinopentanoic acid
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About This Item
Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
174.20
Beilstein:
1725413
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
Product Name
L-Arginine, Vetec™, reagent grade, ≥98%
grade
reagent grade
product line
Vetec™
Assay
≥98%
form
powder
color
white
mp
222 °C (dec.) (lit.)
SMILES string
N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
InChI key
ODKSFYDXXFIFQN-BYPYZUCNSA-N
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Application
- L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.: This study examines the role of L-Arginine in nitric oxide production in diabetic patients, proposing its potential benefits for managing vascular complications in diabetes (Stoian et al., 2024).
Biochem/physiol Actions
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jia-Yi Dong et al.
American heart journal, 162(6), 959-965 (2011-12-06)
Previous studies suggest that L-arginine, an amino acid and a substrate of nitric oxide synthase, may have blood pressure (BP)-lowering effect. Because some studies were performed with limited number of patients with hypertension and therefore limited statistical power with sometimes
Diane N Singhroy et al.
Retrovirology, 10, 73-73 (2013-07-23)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.
Isabelle Dunand-Sauthier et al.
Journal of immunology (Baltimore, Md. : 1950), 193(4), 1690-1700 (2014-07-11)
Arginine, a semiessential amino acid implicated in diverse cellular processes, is a substrate for two arginases-Arg1 and Arg2-having different expression patterns and functions. Although appropriately regulated Arg1 expression is critical for immune responses, this has not been documented for Arg2.
Kaoru Kumazaki et al.
Nature, 509(7501), 516-520 (2014-04-18)
Newly synthesized membrane proteins must be accurately inserted into the membrane, folded and assembled for proper functioning. The protein YidC inserts its substrates into the membrane, thereby facilitating membrane protein assembly in bacteria; the homologous proteins Oxa1 and Alb3 have
Shiroh Futaki et al.
Current pharmaceutical design, 19(16), 2863-2868 (2012-11-13)
Intracellular delivery using cell-penetrating peptides (CPPs) has received considerable attention as a promising method for introducing exogenous molecules into cells. The mechanisms that enable efficient internalization of CPPs together with cargo molecules are also of interest. In this review, we
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