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V900326

Sigma-Aldrich

(+)-Sodium L-ascorbate

Vetec, reagent grade, 98%

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Synonym(s):
L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt
Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
Beilstein:
3767246
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

reagent grade

product line

Vetec

Assay

98%

form

powder

color

white to off-white

mp

220 °C (dec.) (lit.)

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

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General description

Sodium L-ascorbate is an ascorbate derivative.

Biochem/physiol Actions

Sodium L-ascorbate favors apoptosis in urinary bladder carcinoma. It reduces reactive oxygen species generation and plays a role in elastogenesis. In addition, it improves mRNA levels of tropoelastin contributing to skin remodeling. Sodium L-ascorbate may serve as a potential therapeutic potential and may be used in combination with collagenogenesis inhibitorsfor treating dermal scars and keloids. It has wide applications in the food industry as an antioxidant and preservative. Sodium ascorbate also elicits protection by stabilizing membrane, lowering lipid peroxidation and enhancing total antioxidant content.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1


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Vitamin C and Trolox decrease oxidative stress and hemolysis in cold-stored human red blood cells
Czubak K, et al.
Redox Report, 22(6), 445-450 (2017)
Significant overexpression of metallothionein and cyclin D1 and apoptosis in the early process of rat urinary bladder carcinogenesis induced by treatment with N-butyl-N-(4-hydroxybutyl) nitrosamine or sodium L-ascorbate
Takaba K, et al.
Carcinogenesis, 21(4), 691-700 (2000)
Antioxidant role of ascorbic acid and his protective effects on chronic diseases
Oxidative Stress and Chronic Degenerative Diseases-A Role for Antioxidants, 75(3), 449-449 (2013)
A Compendium of Essays on Alternative Therapy (2011)
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic

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