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About This Item
Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
EC Number:
205-126-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3767246
MDL number:
Product Name
(+)-Sodium L-ascorbate, Vetec™, reagent grade, 98%
InChI key
PPASLZSBLFJQEF-RXSVEWSESA-M
InChI
1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
SMILES string
[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
grade
reagent grade
product line
Vetec™
assay
98%
form
powder
color
white to off-white
mp
220 °C (dec.) (lit.)
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Biochem/physiol Actions
Sodium L-ascorbate favors apoptosis in urinary bladder carcinoma. It reduces reactive oxygen species generation and plays a role in elastogenesis. In addition, it improves mRNA levels of tropoelastin contributing to skin remodeling. Sodium L-ascorbate may serve as a potential therapeutic potential and may be used in combination with collagenogenesis inhibitorsfor treating dermal scars and keloids. It has wide applications in the food industry as an antioxidant and preservative. Sodium ascorbate also elicits protection by stabilizing membrane, lowering lipid peroxidation and enhancing total antioxidant content.
General description
Sodium L-ascorbate is an ascorbate derivative.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
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Vitamin C and Trolox decrease oxidative stress and hemolysis in cold-stored human red blood cells
Czubak K, et al.
Redox Report, 22(6), 445-450 (2017)
Significant overexpression of metallothionein and cyclin D1 and apoptosis in the early process of rat urinary bladder carcinogenesis induced by treatment with N-butyl-N-(4-hydroxybutyl) nitrosamine or sodium L-ascorbate
Takaba K, et al.
Carcinogenesis, 21(4), 691-700 (2000)
A Compendium of Essays on Alternative Therapy (2011)
Antioxidant role of ascorbic acid and his protective effects on chronic diseases
Oxidative Stress and Chronic Degenerative Diseases-A Role for Antioxidants, 75(3), 449-449 (2013)
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
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