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Merck
CN

V900238

Diethylene glycol monoethyl ether

Vetec™, reagent grade, 99%

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL™, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
111-90-0
Molecular Weight:
134.17
EC Number:
203-919-7
UNSPSC Code:
12352112
PubChem Substance ID:
329829664
Beilstein/REAXYS Number:
1736441
MDL number:
MFCD00002872
Assay:
99%
Grade:
reagent grade
Bp:
202 °C (lit.)
Vapor pressure:
0.12 mmHg ( 20 °C)

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InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

SMILES string

CCOCCOCCO

grade

reagent grade

vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

product line

Vetec™

assay

99%

form

liquid

expl. lim.

1.2 %, 135 °F, 23.5 %, 182 °F

dilution

(for analytical testing)

impurities

≤0.10% water
water

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

mp

-80 °C (lit.)

density

0.999 g/mL at 25 °C (lit.)

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Legal Information

CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow
Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD8710V
WXBD3016V
WXBD0505V
WXBD0035V
WXBC8052V

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J-L Delongeas et al.
Regulatory toxicology and pharmacology : RTP, 57(2-3), 284-290 (2010-03-30)
Drug safety research is frequently faced with the challenge of the selection of appropriate vehicles for use in in vivo non-clinical safety assessment studies. Reported here are the results of blend Labrasol, Labrafil and Transcutol, [L/L/T, (4/4/2, v/v/v)], excipients used
Rania M Hathout et al.
Molecular pharmaceutics, 7(4), 1266-1273 (2010-06-16)
This research determined the uptake of individual components of topically applied microemulsions into the stratum corneum (SC) and assessed their molecular effects on skin barrier function. The microemulsions comprised oleic acid, Tween20, Transcutol and water. The effects of selected formulations
Jeoung Hee Yoo et al.
Archives of pharmacal research, 33(3), 417-426 (2010-04-03)
Self-nanoemulsifying drug delivery system (SNEDDS) containing oil (Phosal 53 MCT), surfactant (Labrasol), and cosurfactant (Transcutol-HP or Lutrol-E400) was prepared to enhance solubility and dissolution of lutein. Ternary phase diagram of the SNEDDS was constructed to identify the self-emulsifying regions following
Maria Manconi et al.
International journal of pharmaceutics, 412(1-2), 37-46 (2011-05-03)
The ability of a recently developed novel class of liposomes to promote dermal delivery of tretinoin (TRA) was evaluated. New penetration enhancer-containing vesicles (PEVs) were prepared adding to conventional phosphatidylcholine vesicles (control liposomes) different hydrophilic penetration enhancers: Oramix NS10 (OrNS10)
Bhupinder Singh et al.
Drug delivery, 18(8), 599-612 (2011-10-20)
Carvedilol, a widely prescribed cardiovascular drug for hypertension and congestive heart failure, exhibits low and variable bioavailability owing to poor absorption and extensive hepatic first-pass metabolism. The current research work, therefore, entails formulation development of liquid self-nano-emulsifying drug delivery systems
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