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V900134

Sigma-Aldrich

L-Ascorbic acid

Vetec™, reagent grade, 99%

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
200-066-2
MDL number:
MFCD00064328
UNSPSC Code:
12352205
PubChem Substance ID:
329829570

grade

reagent grade

product line

Vetec™

Assay

99%

form

powder

color

white to off-white

mp

190-194 °C (dec.)

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

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General description

Vitamin C is called as ascorbate in the protonated form and as ascorbic acid in neutral state. Vitamin C is synthesized in plants, animals and birds. However, it is not synthesized in mammals and exists as ascorbate.

Application

L-Ascorbic acid has been used in extraction buffer for the isolation of α-tocopherol and β-carotene in napier grass silage and oat silage prior to saponification.

Biochem/physiol Actions

Vitamin C is a potent antioxidant and is reversibly oxidized to dehydroascorbate via an ascorbyl radical intermediate. Vitamin C mediates the synthesis of tryptophan, tyrosine and folic acid as well as collagen and neurotransmitters. It also coordinates metabolism of tyrosine, folic acid and tryptophan, hydroxylation of glycine, proline, lysine carnitine and catecholamine. Vitamin C promotes wound healing, repair and iron absorption. It is a safe anti-pigmenting compound supplement in skin care cosmetics for effective reduction of UV induced pigmentation. Vitamin C is regarded as an effective skin protection agent with anti-aging functionality. Vitamin C deficiency is implicated in scurvy, a haemorrhagic disease. Supplementation with vitamin C prevents scurvy. Vitamin C also helps in treating common cold.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitamin C Prevents Ultraviolet-induced Pigmentation in Healthy Volunteers: Bayesian Meta-analysis Results from 31 Randomized Controlled versus Vehicle Clinical Studies
De Dormael R, et al.
The Journal of Clinical and Aesthetic Dermatology, 12(2), E53-E53 (2019)
Effects of overnight wilting and additives on the fatty acid profile, alpha-tocopherol and beta-carotene of whole plant oat silages
Liu QH, et al.
Anim. Feed Sci. Technol., 114370-114370 (2019)
The effect of fibrolytic enzyme, Lactobacillus plantarum and two food antioxidants on the fermentation quality, alpha-tocopherol and beta-carotene of high moisture napier grass silage ensiled at different temperatures
Liu QH, et al.
Anim. Feed Sci. Technol., 221, 1-11 (2016)
Vitamin C in health and disease: its role in the metabolism of cells and redox state in the brain
Figueroa-Mendez R and Rivas-Arancibia, S
Frontiers in Physiology, 6, 397-397 (2015)
Vitamin C in disease prevention and cure: an overview
Chambial S, et al.
Indian Journal of Clinical Biochemistry : IJCB, 28(4), 314-328 (2013)
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