V900131
CDI
Vetec™, reagent grade, 97%
Synonym(s):
1,1′-Carbonyldiimidazole
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About This Item
Empirical Formula (Hill Notation):
C7H6N4O
CAS Number:
Molecular Weight:
162.15
Beilstein:
6826
EC Number:
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:
Recommended Products
grade
reagent grade
product line
Vetec™
Assay
97%
mp
117-122 °C (lit.)
SMILES string
O=C(n1ccnc1)n2ccnc2
InChI
1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
InChI key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
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Application
CDI can be used:
- To decarboxylate malonic acid derivatives to yield carbonyl imidazole moiety, which can further be reacted with different nucleophiles.
- To activate cellulose membranes, which are used in immunosensor applications.
- To functionalize Fe3O4-SiO2 core-shell nanoparticles for bio-applications.
- To prepare syn- and anti-1,2-imidazolylpropylamines by reacting with syn- and anti-1,2-amino alcohols.
- In the preparation of N-substituted imidazole derivatives, which are further used to prepare new ionic liquids.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Synthesis and surface functionalization of Fe3O4-SiO2 core-shell nanoparticles with 3-glycidoxypropyltrimethoxysilane and 1, 1′-carbonyldiimidazole for bio-applications
Ta TKH, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 504(2), 376-383 (2016)
Regio-and Stereospecific Syntheses of syn-and anti-1, 2-Imidazolylpropylamines from the Reaction of 1, 1′-Carbonyldiimidazole with syn-and anti-1, 2-Amino Alcohols
Mulvihill MJ, et al.
The Journal of Organic Chemistry, 69(15), 5124-5127 (2004)
1, 1′-Carbonyldiimidazole mediates the synthesis of N-substituted imidazole derivatives from Morita--Baylis--Hillman adducts
Rodrigues Jr MT, et al.
Tetrahedron Letters, 55(1), 180-183 (2014)
Daniela Stöllner et al.
Analytical biochemistry, 304(2), 157-165 (2002-05-16)
Methods for the activation of a cellulose dialysis membrane for immunosensor applications have been developed. For activation two reagents, 1,1'-carbonyldiimidazole (CDI) and 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP), were compared with respect to the coupling efficiency for glucose oxidase (GOx) and 1,8-diamino-2,6-dioxaoctane. The
Courtney L Weiner et al.
Journal of anxiety disorders, 32, 66-72 (2015-04-13)
Anxiety disorders constitute the most common mental health disturbance experienced by youth. Sleep-related problems (SRPs) are highly prevalent among anxious youth and encompass a variety of problems including nighttime fears, insomnia, and refusal to sleep alone. Given that chronic sleep
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