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About This Item
Empirical Formula (Hill Notation):
HNO3
CAS Number:
Molecular Weight:
63.01
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
Recommended Products
concentration
65%
SMILES string
O[N+]([O-])=O
InChI
1S/HNO3/c2-1(3)4/h(H,2,3,4)
InChI key
GRYLNZFGIOXLOG-UHFFFAOYSA-N
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General description
Nitric acid is generally used as a primary reagent for the nitration of organic molecules. It is also used as a strong oxidizing agent in organic synthesis to perform the oxidative transformations.
Application
Nitric acid is used as a reagent in:
- The nitration of aromatic compounds, aromatic heterocycles, alkenes, active methylene carbons, etc.
- The oxidation of alcohols, aldehydes, esters, and heteroatoms.
- The aromatization and dehydrogenation reactions.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Ox. Liq. 3 - Skin Corr. 1A
Supplementary Hazards
Storage Class Code
5.1B - Oxidizing hazardous materials
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Nitric Acid
Parker KA, et al.
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2001)
Oxidation of benzylic alcohols and ethers to carbonyl derivatives by nitric acid in dichloromethane
Strazzolini P and Runcio A
European Journal of Organic Chemistry, 2003(3), 526-536 (2003)
Nitric acid in the presence of P2O5 supported on silica gel?a useful reagent for nitration of aromatic compounds under solvent-free conditions
Hajipour AR and Ruoho AE
Tetrahedron Letters, 46(48), 8307-8310 (2005)
Lauren E Kremer et al.
Journal of inorganic biochemistry, 147, 227-234 (2015-05-11)
Uncontrolled reactions in biological media are a main obstacle for clinical translation of V-based anti-diabetic or anti-cancer pro-drugs. We investigated the use of controlled-release pharmaceutical formulations to ameliorate this issue with a series of V(V) and (IV) complexes of anionic
Alyson M Baergen et al.
Environmental science & technology, 47(2), 815-820 (2012-12-15)
The fate of NO(x) (=NO + NO(2)) is important to understand because NO(x) is a significant player in air quality determination through its role in O(3) formation. Here we show that renoxification of the urban atmosphere may occur through the
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