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Safety Information

1601827

USP

Residual Solvent Class 2 - Trichloroethylene

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Trichloroethylene solution, Trichloroethene

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About This Item

CAS Number:
79-01-6
EC Number:
201-167-4
MDL number:
MFCD00000838
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

form

solution

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

single component solution

SMILES string

ClC(=CCl)Cl

InChI

1S/C2HCl3/c3-1-2(4)5/h1H

InChI key

XSTXAVWGXDQKEL-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Residual Solvent Class 2 - Trichloroethylene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

closed cup - does not flash

Flash Point(C)

closed cup - does not flash

Regulatory Information

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Shams Tabrez et al.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 27(3), 178-196 (2009-08-07)
Trichloroethylene (TCE) is a prevalent occupational and environmental contaminant that has been reported to cause a variety of toxic effects. This article reviews toxicity, mutagenicity, and carcinogenicity caused by the exposure of TCE and its metabolites in the living system
Prabhakar Pant et al.
Journal of environmental sciences (China), 22(1), 116-126 (2010-04-20)
Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen
J Christopher Corton
Critical reviews in toxicology, 38(10), 857-875 (2008-09-30)
Trichloroethylene (TCE) is an industrial solvent and a widespread environmental contaminant. Induction of liver cancer in mice by TCE is thought to be mediated by two metabolites, dichloroacetate (DCA) and trichloroacetate (TCA), both of which are themselves mouse liver carcinogens.
David J Jollow et al.
Critical reviews in toxicology, 39(9), 782-797 (2009-10-27)
Trichloroethylene (TCE) is a widespread environmental contaminant that is carcinogenic when given in high, chronic doses to certain strains of mice and rats. The capacity of TCE to cause cancer in humans is less clear. The current maximum contaminant level
Glinda S Cooper et al.
Environmental health perspectives, 117(5), 696-702 (2009-05-30)
Our objective was to examine experimental and epidemiologic studies pertaining to immune-related, and specifically autoimmune-related, effects of trichloroethylene (TCE). We performed a literature search of PubMed and reviewed bibliographies in identified articles. We then systematically reviewed immune-related data, focusing on
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