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Niacin

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Nicotinic acid, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3
Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
Beilstein:
109591
MDL number:
MFCD00006391
UNSPSC Code:
41116107
PubChem Substance ID:
329750552
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nicotinic acid

manufacturer/tradename

USP

technique(s)

HPLC: suitable

mp

236-239 °C (lit.)

solubility

ethanol: 12.5 g/L at 25 °C
water: soluble 180 g/L at 20 °C

density

1.473 g/cm3 at 25 °C

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Niacin USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard, standard stock, system suitability, and standard niacin stock solution during the assay, impurity analysis, and performance test by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
  • Niacin Extended-Release Tablets
  • Niacin
  • Niacin or niacinamide assay
  • Oil- and Water-Soluble Vitamins Capsules
  • Water-Soluble Vitamins Capsules

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oil- and Water-Soluble Vitamins Capsules
United States Pharmacopeia, 40(5), 5389-5389 (2017)
Niacin Extended-Release Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 3141-3141 (2020)
Water-Soluble Vitamins Capsules
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 5499-5499 (2016)
NIACIN OR NIACINAMIDE ASSAY
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5), 6704-6704 (2014)
Niacin
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(5), 3138-3138 (2020)
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