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1397006

USP

Methacycline hydrochloride

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
6-Demethyl-6-deoxy-6-methyleneoxytetracycline monohydrochloride
Empirical Formula (Hill Notation):
C22H22N2O8 · HCl
CAS Number:
3963-95-9
Molecular Weight:
478.88
Beilstein:
5470951
MDL number:
MFCD04972012
UNSPSC Code:
41116107
PubChem Substance ID:
329750384
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

methacycline

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Cl[H].[H][C@@]12[C@@H](O)[C@]3([H])C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1

InChI key

VZQARNDJLLWXGL-CCHMMTNSSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methacycline hydrochloride USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Doxycycline
  • Doxycycline Hyclate Capsules
  • Doxycycline Hyclate
  • Doxycycline for Injection
  • Doxycycline Capsules
  • Doxycycline Tablets
  • Doxycycline for Oral Suspension

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Charles Sinclair et al.
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5151-5159 (2014-04-29)
TCR signaling plays a central role in directing developmental fates of thymocytes. Current models suggest TCR signal duration directs CD4 versus CD8 lineage development. To investigate the role of TCR signaling during positive selection directly, we switched signaling off in

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