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USP

Malic acid

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
DL-Malic acid, (±)-2-Hydroxysuccinic acid, DL-Hydroxybutanedioic acid
Linear Formula:
HO2CCH2CH(OH)CO2H
CAS Number:
6915-15-7
Molecular Weight:
134.09
Beilstein:
1723539
MDL number:
MFCD00064212
UNSPSC Code:
41116107
PubChem Substance ID:
329750312
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

4.6 (vs air)

vapor pressure

<0.1 mmHg ( 20 °C)

API family

malic acid

autoignition temp.

644 °F

manufacturer/tradename

USP

mp

131-133 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(CC(O)=O)C(O)=O

InChI

1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)

InChI key

BJEPYKJPYRNKOW-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Malic acid USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for impurity analysis, specific test and composition according to the given below monographs of United States Pharmacopeia (USP):
  • Malic Acid
  • Alanine

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alanine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(2), 101-101 (2023)
Malic acid
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(6) (2022)
Hugo Oliveira et al.
PloS one, 9(10), e108376-e108376 (2014-10-08)
Resistance rates are increasing among several problematic Gram-negative pathogens, a fact that has encouraged the development of new antimicrobial agents. This paper characterizes a Salmonella phage endolysin (Lys68) and demonstrates its potential antimicrobial effectiveness when combined with organic acids towards
M Taillefer et al.
Applied and environmental microbiology, 81(7), 2423-2432 (2015-01-27)
Clostridium thermocellum produces ethanol as one of its major end products from direct fermentation of cellulosic biomass. Therefore, it is viewed as an attractive model for the production of biofuels via consolidated bioprocessing. However, a better understanding of the metabolic
Jie Chen et al.
BMC plant biology, 15, 28-28 (2015-02-04)
QTLs controlling individual sugars and acids (fructose, glucose, malic acid and tartaric acid) in grape berries have not yet been identified. The present study aimed to construct a high-density, high-quality genetic map of a winemaking grape cross with a complex
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