1372050
USP
Lysophosphatidylcholine
United States Pharmacopeia (USP) Reference Standard
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Synonym(s):
L-α-Lysophosphatidylcholine from egg yolk, 1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
Recommended Products
grade
pharmaceutical primary standard
API family
lysophosphatidylcholine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Lysophosphatidylcholine USP reference standard for use in specified quality tests and assays.
Also used to prepare standard solution for assay in Egg Phospholipids by Liquid Chromatography in conjunction with evaporative light-scattering detector according to United States Pharmacopeia(USP).
Also used to prepare standard solution for assay in Egg Phospholipids by Liquid Chromatography in conjunction with evaporative light-scattering detector according to United States Pharmacopeia(USP).
Biochem/physiol Actions
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
related product
Product No.
Description
Pricing
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Egg Phospholipids
United States Pharmacopeia, 33(4), 5755-5755 (2018)
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