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Merck
CN

1354309

USP

Ivermectin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

22,23-Dihydroavermectin B1, MK-933

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About This Item

CAS Number:
70288-86-7
NACRES:
NA.24
PubChem Substance ID:
329750214
UNSPSC Code:
41116107
MDL number:
MFCD00869511

Key Documents

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Product Name

Ivermectin, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1

SMILES string

[H][C@@]1(O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/CO[C@]7([H])[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]67O)O2)[C@@H](C)CC

InChI key

AZSNMRSAGSSBNP-XPNPUAGNSA-N

grade

pharmaceutical primary standard

API family

ivermectin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Ivermectin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solution for the assay and impurity analysis by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP) :
  • Ivermectin Paste
  • Ivermectin Compounded Oral Solution, Veterinary
  • Ivermectin Topical Solution
  • Ivermectin Injection

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Ivermectin Paste
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(5), 2473-2473 (2013)
Ivermectin Topical Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(5), 2476-2476 (2013)
Ivermectin Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(5), 2472-2472 (2018)
Ivermectin Compounded Oral Solution, Veterinary
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 2473-2473 (2019)

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