1301007
USP
Guaifenesin
United States Pharmacopeia (USP) Reference Standard
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Synonym(s):
Guaiacol glyceryl ether, 3-(o-Methoxyphenoxy)-1,2-propanediol, Glycerol guaiacolate, Guaifenesin
Empirical Formula (Hill Notation):
C10H14O4
CAS Number:
Molecular Weight:
198.22
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
guaifenesin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
COc1ccccc1OCC(O)CO
InChI
1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3
InChI key
HSRJKNPTNIJEKV-UHFFFAOYSA-N
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Guaifenesin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Robert R Fayzullin et al.
Journal of pharmaceutical sciences, 103(10), 3176-3182 (2014-08-06)
The solubility of 3-(2-methoxyphenoxy)-propane-1,2-diol, the well-known chiral drug guaifenesin 1, in water has been investigated by means of polythermal and isothermal approaches. It was found that the solubilities of racemic and enantiomeric diols rac- and (R)-1 depend strongly on temperature.
William Storms et al.
Current allergy and asthma reports, 9(2), 101-106 (2009-02-13)
Mucus in the airways is a complex mixture of water, lipids, glycoproteins, sugars, and electrolytes that serves as a lubricant for the epithelium. The efficient flow of respiratory mucus is a first level of immune defense that requires an appropriate
Stephen Bennett et al.
Journal of alternative and complementary medicine (New York, N.Y.), 10(6), 967-969 (2005-01-28)
Ephedrine and guaifenesin are herbal supplements that have experienced increased use over the past decade. Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in many antitussives
Clinical inquiries. Is guaifenesin safe during pregnancy?
Roberto Silva et al.
The Journal of family practice, 56(8), 669-670 (2007-08-03)
Brian C Gilger et al.
Veterinary ophthalmology, 17 Suppl 1, 23-30 (2013-08-06)
To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation. Retrospective study. ESMC implants (1.2 cm length, 30% wt/wt cyclosporine
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