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Merck
CN

1286413

USP

Frovatriptan succinate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Frovatriptan succinate monohydrate, Frovatriptan succinate, R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate

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S59049-5MG
¥2,187.47

¥2,187.47


Estimated to ship on2025年5月27日Details


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S59049-5MG
¥2,187.47

About This Item

Empirical Formula (Hill Notation):
C14H17N3O · C4H6O4 · H2O
CAS Number:
Molecular Weight:
379.41
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

¥2,187.47


Estimated to ship on2025年5月27日Details


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grade

pharmaceutical primary standard

API family

frovatriptan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O

InChI

1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1

InChI key

CUETXFMONOSVJA-KLQYNRQASA-N

Gene Information

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This Item
D0627A6885M7510
assay

≥97% (HPLC)

assay

≥96% (HPLC)

assay

≥98.0% (HPLC)

assay

≥95%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 10 mg/mL

solubility

H2O: 10 mg/mL

color

white

color

off-white

color

white

color

white

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Frovatriptan succinate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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