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1286005

USP

Folic acid

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
PteGlu, Pteroyl-L-glutamic acid, Vitamin M
Empirical Formula (Hill Notation):
C19H19N7O6
CAS Number:
59-30-3
Molecular Weight:
441.40
Beilstein:
100781
MDL number:
MFCD00079305
UNSPSC Code:
41116107
PubChem Substance ID:
329749907
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

folic acid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Folic acid USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard, standard stock, system suitability stock and system suitability solution during the assay, identification, impurity analysis, and performance test by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
  • Folic Acid Tablets
  • Folic Acid assay
  • Folic Acid Compounded Oral Solution
  • Folic Acid

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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WGK

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Folic Acid Compounded Oral Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5), 2027-2027 (2017)
Folic Acid
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 29(2), 2026-2026 (2020)
Folic Acid assay
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(3), 6689-6689 (2022)
Folic Acid Tablets
United States Pharmacopeia, 48(3), 2028-2028 (2022)
Susanna Kariluoto et al.
International journal of food microbiology, 176, 38-48 (2014-02-25)
The objective was to study folate production of yeast strains, bacteria isolated from oat bran, and selected lactic acid bacteria as well as one propionibacterium in oat and barley based models. Simultaneously, we aimed at sustaining the stability of viscosity
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