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1269403

USP

Fenbendazole

Name: Fenbendazole
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₃N₃O₂S

CAS Number:

43210-67-9

Molecular Weight:

299.35

Beilstein:

759077

MDL number:

MFCD00144301

UNSPSC Code:

41116107

PubChem Substance ID:

329749834

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

fenbendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

HDDSHPAODJUKPD-UHFFFAOYSA-N

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Related Categories

Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fenbendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Oxfendazole

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

1269414

1269425

BP692

Fenbendazole, British Pharmacopoeia (BP) Reference Standard

PHR2862

PHR2863

Pictograms

GHS08,GHS09

Signal Word

Warning

Hazard Statements

H361fd,H373,H410

Precautionary Statements

P202 - P260 - P273 - P280 - P308 + P313 - P391

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

Target Organs

Liver,lymph node,Stomach,Nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Biologic effects of fenbendazole in rats and mice: a review.

David Villar et al.

Journal of the American Association for Laboratory Animal Science : JAALAS, 46(6), 8-15 (2007-11-13)

This review summarizes findings from toxicologic, carcinogenic, immunologic, and metabolic studies on fenbendazole (FBZ). Currently, FBZ is used to treat or prevent pinworm outbreaks in laboratory rodents. Because antiparasitic treatments usually are not part of experimental designs, interactions from the

Epidemiology. Opposite effects of anthelmintic treatment on microbial infection at individual versus population scales.

Vanessa O Ezenwa et al.

Science (New York, N.Y.), 347(6218), 175-177 (2015-01-13)

Parasitic worms modulate host immune responses in ways that affect microbial co-infections. For this reason, anthelmintic therapy may be a potent tool for indirectly controlling microbial pathogens. However, the population-level consequences of this type of intervention on co-infecting microbes are

Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: pharmacological implications.

Bettencourt P S Capece et al.

Veterinary journal (London, England : 1997), 181(3), 241-250 (2009-01-07)

Albendazole and fenbendazole are methylcarbamate benzimidazole anthelmintics extensively used to control gastrointestinal parasites in domestic animals. These parent compounds are metabolised to albendazole sulfoxide and fenbendazole sulfoxide (oxfendazole), respectively. Both sulfoxide derivatives are anthelmintically active and are manufactured for use

Development and validation of an ultra high performance liquid chromatography tandem mass spectrometry method for simultaneous determination of sulfonamides, quinolones and benzimidazoles in bovine milk.

Xiao-Lin Hou et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 962, 20-29 (2014-06-03)

A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 38 veterinary drugs (18 sulfonamides, 11 quinolones and 9 benzimidazoles) and 8 metabolites of benzimidazoles in bovine milk by ultra high performance liquid chromatography-positive electrospray ionization

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