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USP

Epilactose

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
4-O-β-D-Galactopyranosyl-D-mannose
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

epilactose

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5-,6-,7-,8+,9+,10-,11-,12+/m1/s1

InChI key

DKXNBNKWCZZMJT-QMRWEYQWSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Epilactose USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as:
  • Lactulose Concentrate
  • Lactulose Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mariko Miyasato et al.
Bioscience, biotechnology, and biochemistry, 68(10), 2086-2090 (2004-10-27)
The regioselectivity of beta-galactosidase derived from Bacillus circulans ATCC 31382 (beta-1,3-galactosidase) in transgalactosylation reactions using D-mannose as an acceptor was investigated. This D-mannose associated regioselectivity was found to be different from reactions using either GlcNAc or GalNAc as acceptors, not
Wataru Saburi et al.
Bioscience, biotechnology, and biochemistry, 74(8), 1736-1737 (2010-08-12)
A practical purification method for a non-digestible disaccharide, epilactose (4-O-beta-galactosyl-D-mannose), was established. Epilactose was synthesized from lactose with cellobiose 2-epimerase and purified by the following procedure: (i) removal of lactose by crystallization, (ii) hydrolysis of lactose by beta-galactosidase, (iii) digestion
Megumi Nishimukai et al.
Journal of agricultural and food chemistry, 56(21), 10340-10345 (2008-10-08)
Epilactose (4-O-beta-galactopyranosyl-D-mannnose) is a rare disaccharide in cow milk that can be synthesized from lactose by the cellobiose 2-epimerase of Ruminococcus albus. In this study, we examined the biological activities of epilactose using male Wistar-ST rats. The apparent rates of
Hiroki Sato et al.
Bioscience, biotechnology, and biochemistry, 76(8), 1584-1587 (2012-08-11)
Cellobiose 2-epimerase (CE) efficiently forms epilactose which has several beneficial biological functions. A thermostable CE from Rhodothermus marinus was immobilized on Duolite A568 and packed into a column. Lactose (100 g/L) was supplied to the reactor, kept at 50 °C
J Watanabe et al.
Journal of dairy science, 91(12), 4518-4526 (2008-11-29)
We recently reported that cellobiose 2-epimerase from Ruminococcus albus effectively converted lactose to epilactose. In this study, we examined the biological effects of epilactose on intestinal microbiota, bile acid metabolism, and postadministrative plasma glucose by animal tests. Dietary supplementation with

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