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Merck
CN

1227006

USP

Doxylamine succinate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Doxylamine succinate salt

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About This Item

Empirical Formula (Hill Notation):
C17H22N2O · C4H6O4
CAS Number:
562-10-7
Molecular Weight:
388.46
NACRES:
NA.24
PubChem Substance ID:
329749682
UNSPSC Code:
41116107
MDL number:
MFCD00056168

Key Documents

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Product Name

Doxylamine succinate, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

SMILES string

OC(=O)CCC(O)=O.CN(C)CCOC(C)(c1ccccc1)c2ccccn2

InChI key

KBAUFVUYFNWQFM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

doxylamine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... HRH1(3269)

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Doxylamine succinate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, and Pseudoephedrine Hydrochloride Oral Solution
  • Doxylamine Succinate
  • Doxylamine Succinate Oral Solution
  • Doxylamine Succinate Tablets

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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[Nontraumatic rhabdomyolysis due to oral poisoning by doxylamine succinate].
C Paytubí Garí et al.
Medicina clinica, 108(9), 356-356 (1997-03-08)
Safety assessment of OTC drugs: doxylamine succinate.
J A Skare et al.
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 17, 326-340 (1995-01-01)

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