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1134030

USP

Ciclopirox olamine

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolammonium salt
Empirical Formula (Hill Notation):
C12H17NO2 · C2H7NO
CAS Number:
41621-49-2
Molecular Weight:
268.35
MDL number:
MFCD00078997
UNSPSC Code:
41116107
PubChem Substance ID:
329749395
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ciclopirox

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NCCO.CC1=CC(=O)N(O)C(=C1)C2CCCCC2

InChI

1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2

InChI key

MBRHNTMUYWQHMR-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ciclopirox olamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

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Pricing

C2162700

Ciclopirox olamine, European Pharmacopoeia (EP) Reference Standard

C2162702

Ciclopirox impurity B, European Pharmacopoeia (EP) Reference Standard

C2162701

Ciclopirox impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000040

Ciclopirox, European Pharmacopoeia (EP) Reference Standard

1134040

Ciclopirox Related Compound B, United States Pharmacopeia (USP) Reference Standard

1134018

Ciclopirox, United States Pharmacopeia (USP) Reference Standard

1134084

Ciclopirox Related Compound C, United States Pharmacopeia (USP) Reference Standard

1134029

Ciclopirox Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR1920

Ciclopirox, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2854

Ciclopirox Related Compound B, certified reference material, pharmaceutical secondary standard

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pharmaceutical development and technology, 20(2), 197-203 (2013-11-30)
With the aim of reducing system absorption and consequently, the side effects, and simultaneously select a penetration enhancing, three topical formulations with 0.5% ciclopirox olamine (CO) and 15% of propylene glycol (PG), ethoxydiglycol or oleic acid were developed and evaluated
Keita Sugiura et al.
Antimicrobial agents and chemotherapy, 58(7), 3837-3842 (2014-04-23)
Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. Keratin affinity of topical drugs is an important physicochemical property impacting therapeutic efficacy.
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Molecular pharmaceutics, 11(7), 1991-1996 (2014-02-05)
Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. Hence, high efficacy of the active ingredient without systemic

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