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Chloroquine Related Compound A

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
4,7-Dichloroquinoline
Empirical Formula (Hill Notation):
C9H5Cl2N
CAS Number:
86-98-6
Molecular Weight:
198.05
Beilstein:
125359
MDL number:
MFCD00006774
UNSPSC Code:
41116107
PubChem Substance ID:
329749321
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

USP

vapor pressure

0.0000811 kPa ( 25 °C)

API family

chloroquine

form

crystalline

packaging

pkg of 15 mg
pkg of 25 mg

manufacturer/tradename

USP

color

off-white to brown-yellowish

bp

298.4 °F (148°C)

mp

81-83 °C (lit.)

solubility

ethanol: freely soluble
ether: freely soluble
water: slightly soluble

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Clc1ccc2c(Cl)ccnc2c1

InChI

1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H

InChI key

HXEWMTXDBOQQKO-UHFFFAOYSA-N

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Related Categories

General description

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Application

Chloroquine Related Compound A can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315,H317,H319,H411

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)
Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)

Protocols

Chloroquine Phosphate HPLC Assay & Impurity Profiling

Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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