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1012553

USP

Albendazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O2S
CAS Number:
54965-21-8
Molecular Weight:
265.33
MDL number:
MFCD00083232
UNSPSC Code:
41116107
PubChem Substance ID:
329748945
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

albendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Albendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Albendazole Oral Suspension
  • Albendazole Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H361d,H373,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

Target Organs

Adrenal gland,Blood,male reproductive organs,spleen

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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J Horton
Parasitology, 121 Suppl, S113-S132 (2001-06-02)
This comprehensive review briefly describes the history and pharmacology of albendazole as an anthelminthic drug and presents detailed summaries of the efficacy and safety of albendazole's use as an anthelminthic in humans. Cure rates and 0% egg reduction rates are
C M Creţu et al.
Chirurgia (Bucharest, Romania : 1990), 107(1), 15-21 (2012-04-07)
Cystic echinococcosis is parasitic disease due to the larval stage of the metacestode Echinococcus granulosus in the liver (80%), lungs, kidneys, spleen, myocardium etc. Humans are accidental intermediate hosts. Diagnosis is based on laboratory and imaging studies. Treatment is multimodal
John Horton
Fundamental & clinical pharmacology, 17(2), 205-212 (2003-04-02)
Twenty years after the first cases of echinococcal disease were treated with albendazole, it has become an important component in the overall management of both cystic and alveolar echinococcosis. This paper reviews some of the key steps and issues facing
Marlieke E A de Kraker et al.
Tropical medicine & international health : TM & IH, 11(5), 718-728 (2006-04-28)
To determine the efficacies of combinations of ivermectin or diethylcarbamazine and albendazole, which are recommended for use in mass treatment programmes against lymphatic filariasis. Review of published trends in microfilarial (mf) intensities after treatment with these combination therapies. By fitting
John Horton
Current opinion in infectious diseases, 15(6), 599-608 (2003-06-25)
It is over 25 years ago since the original animal research was conducted into albendazole. This review highlights some important steps in fundamental research and the management of helminth disease that have occurred in the past year, appearing in the
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