1005706
USP
Glacial acetic acid
United States Pharmacopeia (USP) Reference Standard
Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Acetic acid, Ethanoic acid, Methanecarboxylic acid, Glacial acetic acid
Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
Beilstein:
506007
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
vapor density
2.07 (vs air)
API family
glacial acetic acid
autoignition temp.
800 °F
expl. lim.
16 %, 92 °F
4 %, 59 °F
manufacturer/tradename
USP
technique(s)
gas chromatography (GC): suitable
refractive index
n20/D 1.371 (lit.)
bp
117-118 °C (lit.)
mp
16.2 °C (lit.)
density
1.049 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
CC(O)=O
InChI
1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChI key
QTBSBXVTEAMEQO-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
General description
Glacial acetic acid is the trivial name used to describe pure acetic acid in an anhydrous state. It is a clear and hygroscopic weak acid, typically available in concentrations ranging from 99.5% to 100%. The name "glacial" refers to the ice-like crystals that form at a temperature slightly below room temperature (16.6°C or 61.9°F), like the German term "Eisessig" (ice-vinegar). Despite being classified as a weak acid, glacial acetic acid is a corrosive poison that can cause harm or even be fatal when in contact with human tissue. Improper storage and handling of glacial acetic acid can pose inherent risks and may lead to patient injuries if not appropriately diluted. Acetic acid/acetate is a common counter ion in peptide preparations.
Glacial acetic acid USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Glacial acetic acid USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Glacial acetic acid USP reference standard for use in specified quality tests and assays. It is also used to prepare standard solution by using liquid chromatography coupled to a UV detector according to the general chapter of United States Pharmacopeia (USP). Based directly on official monographs published in the USP-NF, these highly characterized physical specimens are used in testing by pharmaceutical and related industries to help ensure the identity, strength, quality, and purity of peptide-based medicines.
Further information is available in the general chapter, 503- ACETIC ACID IN PEPTIDES, USP43-NF38 - 6741 of the USP (United States Pharmacopeia).
Further information is available in the general chapter, 503- ACETIC ACID IN PEPTIDES, USP43-NF38 - 6741 of the USP (United States Pharmacopeia).
Other Notes
This product is part of the USP Biologics program.
Sales restrictions may apply.
related product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
WGK
WGK 1
Regulatory Information
危险化学品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
ACETIC ACID IN PEPTIDES
USP43-NF38 - 6741:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5) (2017)
Glacial Acetic Acid Adverse Events: Case Reports and Review of the Literature
Doles W, et al.
Hospital pharmacy (2015)
Takashi Taniguchi et al.
Arthritis & rheumatology (Hoboken, N.J.), 67(2), 517-526 (2014-11-12)
Fli-1, a potential predisposing factor for systemic sclerosis (SSc), is constitutively down-regulated in the lesional skin of patients with SSc by an epigenetic mechanism. To investigate the impact of Fli-1 deficiency on the induction of an SSc phenotype in various
Isabelle Brunet et al.
The Journal of clinical investigation, 124(7), 3230-3240 (2014-06-18)
Autonomic sympathetic nerves innervate peripheral resistance arteries, thereby regulating vascular tone and controlling blood supply to organs. Despite the fundamental importance of blood flow control, how sympathetic arterial innervation develops remains largely unknown. Here, we identified the axon guidance cue
Ilse Cleenwerck et al.
International journal of food microbiology, 125(1), 2-14 (2008-02-02)
Acetic acid bacteria are Gram-negative, obligate aerobic bacteria that have the ability to incompletely oxidize alcohols or sugars to organic acids as end products. They are widespread in nature and most of them are capable to oxidize ethanol as substrate
Protocols
Science Slam panel: Leading gene therapy developers discuss commercialization challenges and the importance of robust process development plans.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service