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Merck
CN

Y0002261

N-Nitroso-dibutylamine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

N-Nitrosodi-n-butylamine solution, Dibutyl nitrosamine

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About This Item

CAS Number:
UNSPSC Code:
41116107
NACRES:
NA.24
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Product Name

N-Nitroso-dibutylamine, European Pharmacopoeia (EP) Reference Standard

SMILES string

N(N=O)(CCCC)CCCC

InChI

1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3

InChI key

YGJHZCLPZAZIHH-UHFFFAOYSA-N

grade

pharmaceutical primary standard (

)

manufacturer/tradename

EDQM

concentration

in methanol

storage temp.

2-8°C

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Application

N-Nitroso-dibutylamine (NDBA) EP reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

It is also used to prepare N-Nitrosamines spiking solution to detect the concentration of NDBA in active substances by chromatography methods in conjunction with mass spectrometer according to the monograph 20542 of European Pharmacopoeia.

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.

This product is provided as delivered and specified by the issuing Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazardExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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N-NITROSAMINES IN ACTIVE SUBSTANCES
European pharmacopoeia, 20542-20542 (2022)

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