InChI key
JWBOIMRXGHLCPP-UHFFFAOYSA-N
InChI
1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
SMILES string
ClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl
grade
analytical standard
packaging
ampule of 250 mg
manufacturer/tradename
Chem Service, Inc. PS-694
Gene Information
rat ... Ar(24208)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Akira Takeshita et al.
The Journal of endocrinology, 216(3), 297-305 (2012-11-28)
Adrenocortical carcinoma (ACC) is a rare disease with an extremely poor prognosis. Mitotane alone or in combination with other cytotoxic drugs is a common therapeutic option for ACC. In addition to its adrenolytic function, mitotane has been known for decades
Liana Tripto-Shkolnik et al.
The Journal of clinical endocrinology and metabolism, 98(2), 443-447 (2013-01-01)
Adrenocortical carcinoma (ACC) affects patients in a broad age group, including young women. Mitotane, an adrenolytic agent, is the mainstay of treatment after surgical removal of the tumor. There is extreme paucity of information regarding the effect of mitotane on
S Ederhy et al.
Journal of endocrinological investigation, 35(10), 911-914 (2012-09-28)
We designed a single-center retrospective study to assess the QT interval duration and to describe cardio vascular events among patients treated with mitotane for a adrenocortical carcinoma (ACC). We selected 14 patients (6 males and 8 females) that met the
Adrienn Zsippai et al.
Pharmacogenomics, 13(12), 1351-1361 (2012-09-13)
The adrenolytic agent mitotane is widely used in the treatment of adrenocortical cancer; however, its mechanism of action is poorly elucidated. We have studied mitotane-induced mRNA expression changes in the NCI-H295R adrenocortical cancer cell line. Cell viability and hormone assays
Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
A Berruti et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 23 Suppl 7, vii131-vii138 (2012-11-20)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service