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About This Item
Empirical Formula (Hill Notation):
C2H8NO2PS
CAS Number:
Molecular Weight:
141.13
EC Number:
233-606-0
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
8137714
MDL number:
InChI key
NNKVPIKMPCQWCG-UHFFFAOYSA-N
InChI
1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4)
SMILES string
COP(N)(=O)SC
grade
analytical standard
packaging
ampule of 100 mg
manufacturer/tradename
Chem Service, Inc. PS-676
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
format
neat
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General description
Methamidophos is a nonselective type of organophosphorus insecticide and a potent acetylcholinesterase inhibitor, which is commonly used in controlling a broad spectrum of pest insects such as chewing and sucking insects and spider mites on citrus fruits, ornamental plants, stone fruits and other intensive agricultural crops.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
413.6 °F - closed cup
flash_point_c
212 °C - closed cup
Regulatory Information
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Titanium dioxide mediated photocatalytic degradation of methamidophos in aqueous phase.
Wei L, et al.
Journal of Hazardous Materials, 164(1), 154-160 (2009)
Guilherme L Emerick et al.
Toxicology, 292(2-3), 145-150 (2011-12-27)
The current Organisation for Economic Co-operation and Development (OECD) guidelines for evaluating organophosphorus-induced delayed neuropathy (OPIDN) require the observation of dosed animals over several days and the sacrifice of 48 hens. Adhering to these protocols in tests with enantiomers is
Exposure to methamidophos at adulthood adversely affects serotonergic biomarkers in the mouse brain.
Carla S Lima et al.
Neurotoxicology, 32(6), 718-724 (2011-08-30)
Epidemiologic studies describe a potential risk of depression and suicide in farm workers exposed to organophosphates (OPs). In a previous study we observed an increase in depressive-like behavior in adult mice exposed to the OP pesticide methamidophos. Considering the association
Teresa Rodríguez et al.
Occupational and environmental medicine, 69(2), 119-125 (2011-07-05)
This study assessed pesticide exposure of children in rural Nicaragua in relation to parental pesticide use, from around conception to current school age, as part of an epidemiological evaluation of neurodevelopment effects. We included 132 children whose parents were subsistence
Bao-Jian Hang et al.
Applied and environmental microbiology, 78(6), 1962-1968 (2012-01-17)
De-esterification is an important degradation or detoxification mechanism of sulfonylurea herbicide in microbes and plants. However, the biochemical and molecular mechanisms of sulfonylurea herbicide de-esterification are still unknown. In this study, a novel esterase gene, sulE, responsible for sulfonylurea herbicide
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