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Safety Information

PS51

Dimethylarsinic acid

analytical standard

Synonym(s):

Cacodylic acid, Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide

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About This Item

Linear Formula:
(CH3)2As(O)OH
CAS Number:
Molecular Weight:
138.00
Beilstein:
1736965
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:

grade

analytical standard

packaging

ampule of 500 mg

manufacturer/tradename

Chem Service, Inc. PS51

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

C[As](C)(O)=O

InChI

1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)

InChI key

OGGXGZAMXPVRFZ-UHFFFAOYSA-N

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General description

Dimethylarsinic acid is a nonselective type of herbicide and a metabolite of inorganic arsenic, which is used to defoliate or desiccate a wide variety of plants.

Application

Dimethylarsinic acid (DMA) may be used as a reference standard for the determination of dimethylarsinic acid (DMA) in fish tissues and urine samples by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC/ICP/MS).
Dimethylarsinic acid may be used as a reference standard in the determination of dimethylarsinic acid in urine samples using gas chromatography coupled with ion trap mass spectrometry (GC-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Determination of As (III), As (V), monomethylarsonic acid, dimethylarsinic acid and arsenobetaine by HPLC-ICP-MS: analysis of reference materials, fish tissues and urine.
Wrobel k, et al.
Talanta, 58(5), 899-907 (2002)
Sittig's Handbook of Pesticides and Agricultural Chemicals (2013)
Cancer induction by an organic arsenic compound, dimethylarsinic acid (cacodylic acid), in F344/DuCrj rats after pretreatment with five carcinogens.
Yamamoto S, et al.
Cancer Research, 55(6), 1271-1276 (1995)
Speciation of dimethylarsinic acid and monomethylarsonic acid by solid-phase microextraction?gas chromatography?ion trap mass spectrometry.
Mester Z and Pawliszyn J
Journal of Chromatography A, 873(1), 129-135 (2000)
Yongyong Hou et al.
Environmental health perspectives, 121(2), 237-243 (2012-12-12)
There is growing evidence that chronic exposure to inorganic arsenic (iAs) is associated with an increased prevalence of type 2 diabetes (T2D). However, the mechanisms for the diabetogenic effect of iAs are still largely unknown. White adipose tissue (WAT) actively

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