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Safety Information

PS2075

Azadirachtin

technical mixture, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C35H44O16
CAS Number:
11141-17-6
Molecular Weight:
720.71
MDL number:
MFCD00083241
UNSPSC Code:
41116107
PubChem Substance ID:
24899162

grade

analytical standard

packaging

ampule of 10 mg

manufacturer/tradename

Chem Service, Inc. PS-2075

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

[H]C1([H])C2OC3([H])OC=CC3(O)C1C4(C)OC24[C@@]5(C)[C@@H](O)[C@@H]6OC[C@]7([C@H](C[C@H](OC(=O)C(C)=CC)[C@]8(COC(O)([C@H]58)C(=O)OC)[C@@]67[H])OC(C)=O)C(=O)OC

InChI

1S/C35H44O16/c1-8-15(2)24(38)49-18-12-19(48-16(3)36)32(26(39)43-6)13-46-21-22(32)31(18)14-47-34(42,27(40)44-7)25(31)29(4,23(21)37)35-20-11-17(30(35,5)51-35)33(41)9-10-45-28(33)50-20/h8-10,17-23,25,28,37,41-42H,11-14H2,1-7H3/t17?,18-,19?,20?,21+,22+,23?,25?,28?,29?,30?,31?,32-,33?,34-,35?/m0/s1

InChI key

FTNJWQUOZFUQQJ-CFYAVYSVSA-N

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General description

Crude extract of the neem tree. Not intended for use as a quantitative standard

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Susana Grimalt et al.
Journal of agricultural and food chemistry, 59(15), 8070-8077 (2011-07-06)
A rapid and sensitive LC-ESI-MS method has been developed and validated for the quantitation of azadirachtin and 3-tigloylazadirachtol in deciduous tree matrices. The method involves automated extraction and simultaneous cleanup using an accelerated solvent technique with the matrix dispersed in
Smita Srivastava et al.
Applied biochemistry and biotechnology, 167(6), 1818-1830 (2012-01-17)
The vast untapped potential of hairy root cultures as a stable source of biologically active chemicals has focused the attention of scientific community toward its commercial exploitation. However, the major bottleneck remains its successful scale-up. Due to branching, the roots
Bruna Dallaqua et al.
Journal of ethnopharmacology, 143(3), 805-811 (2012-08-28)
The role of Azadirachta indica (neem) against Chagas disease and its antibiotic and antidiabetic action have been demonstrated in non-pregnant animals. However, the effects of neem on lipid metabolism and oxidative stress during pregnancy remain to be investigated. The objective
Smita Srivastava et al.
Bioprocess and biosystems engineering, 35(9), 1549-1553 (2012-05-15)
Present investigation involves hairy root cultivation of Azadirachta indica in a modified stirred tank reactor under optimized culture conditions for maximum volumetric productivity of azadirachtin. The selected hairy root line (Az-35) was induced via Agrobacterium rhizogenes LBA 920-mediated transformation of
Saurav Kumar et al.
Fish & shellfish immunology, 34(2), 564-573 (2012-12-25)
Modulation of the immune responses using active bio-ingredients as a possible prophylaxis measure has been novel prospect for aquaculture. The present study evaluated the effects of azadirachtin EC 25% on non-specific immune responses in goldfish Carassius auratus and resistance against
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