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Safety Information

PHL82582

Lycorine hydrochloride

phyproof® Reference Substance

Synonym(s):

Amarylline hydrochloride, Narcissine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H17NO4 · HCl
CAS Number:
2188-68-3
Molecular Weight:
323.77
MDL number:
MFCD00243111
UNSPSC Code:
12352202
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages
pharmaceutical

storage temp.

2-8°C

SMILES string

Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@H]([C@@H]1O)[C@@H]23

InChI

1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChI key

VUVNTYCHKZBOMV-NVJKKXITSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
137153
120346
113881

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