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Carboxen® 569 Carbon Adsorbent

20-45 mesh

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Synonym(s):
Carboxen® Adsorbent
UNSPSC Code:
23201100
NACRES:
SB.54

product name

CARBOXEN® 569, 20-45 MESH,

description

Surface pH = 8.6

Quality Level

100

technique(s)

LPLC: suitable

surface area

500 m2/g

pore size

23 % macroporosity
32 % mesoporosity
45 % microporosity

storage temp.

room temp

General description

Carboxens are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables. Tapered pores result in increased thermodynamic and kinetic properties for both adsorption and desorption. The Carboxens vary in the relative percentage of pore structures (micro, meso, and macro), surface area, and surface pH.

Application

Carboxens® are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables.

Features and Benefits

Features and Benefits:

  • Spherical
  • Hard (ball pan hardness >98%)
  • Stable up to 400°C
  • High purity
  • Easy to pack
  • Stable over entire pH range
  • Do not create backpressure
  • High osmotic shock stability
  • Tapered pore sizing (from macro- to meso- to micro-)

Other Notes

For more information, please visit: specialty Carbon Adsorbents

Legal Information

Carboxen isa registered trademark of Sigma-Aldrich Co. LLC
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Synthetic Carbon Adsorbents for Host Cell Protein Removal in Monoclonal Antibody Purification

Demonstration of the excellent capability of Carboxen® synthetic carbon adsorbents to reduce host cell proteins (HCPs) and recover monoclonal antibodies (mAbs) using a post protein A pool step.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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